167 patients with FTLD syndromes (43 bvFTD, 28 nfvPPA, 18 svPPA, 36 PSP, 32 CBS, 10 ALS-FTD), of whom 70 pathology-proven (50 FTLD-tau, 18 FTLD-TDP, 2 FTLD-FUS), 43 AD patients, 55 HCs. The gene discussed is MAPT; the disease is Alzheimer disease.