We found that constitutive deletion of the Nfat1 gene did not affect T-ALL onset in both the transgenic TEL-JAK2 and in the BM transplantation model of ICN1-induced T-ALL (S1 Fig), suggesting either no function or a redundant of Nfat genes in T-ALL. The gene discussed is NFATC2; the disease is acute lymphoblastic leukemia.