NFATC2 and acute lymphoblastic leukemia: To gain insight into the molecular basis of NFAT oncogenic properties, we compared the transcriptome of Nfat-proficient and Nfat-deficient leukemic cells, obtained as described in Fig 1A, using 3 independent ICN1; RCT2; Nfat1-/-; Nfat2fl/fl; Nfat4fl/fl T-ALL.