PIAS2 and Platelet storage pool disease: To determine the involvement of PIAS2 in sPD, WT, Ifnb–/–, and Ifnar1–/– mice were injected with AAVs vectors that overexpress PIAS2-mCherry or mCherry-only under the neuron-specific SYN1 promoter in the SN and frontal cortex of the brain.