AFP and neoplasm: The multivariate Cox regression analysis, PT (HR = 2.246, 95%CI: 2.246–1.118, P = 0.023), AFP (> 400 ng/ml vs. ≤ 20 ng/ml: HR = 4.091, 95%CI: 1.715–9.760, P = 0.001) and tumor diameter (HR = 1.123, 95%CI: 1.038–1.216, P = 0.004) were determined to be the independent prognostic factors for OS, HBV infection (HR = 1.858, 95%CI: 1.000–3.458, P = 0.05), AFP (> 400 ng/ml vs. ≤ 20 ng/ml: HR = 2.199, 95%CI: 1.265–3.820, P = 0.005), MVI presence (HR = 1.780, 95%CI: 1.085–2.920, P = 0.022) and tumor diameter (HR = 1.072, 95%CI: 1.010–1.138, P = 0.023) for RFS (Table 2).