The top 10 most overrepresented pathways in the ARC were antigen presentation pathway, autoimmune thyroid disease signaling, allograft rejection signaling, B Cell development, OX40 signaling pathway, Cdc42 signaling, graft-versus-host disease signaling, Type I Diabetes Mellitus signaling, neuroinflammation signaling pathway, and Nur77 signaling in T Lymphocytes. This evidence concerns the gene NR4A1 and type 1 diabetes mellitus.