CRP and COVID-19: In another study, the authors proposed that a diagnostic criterion including peripheral blood oxygen saturation to the fraction of inspired oxygen (SpO2/FiO2), CRP, ferritin, cytokines/chemokines, and neutrophil/lymphocyte ratio may have a strong diagnostic power for COVID-CS.102 Mehta et al.13 proposed that prospective screening for hyperinflammation using laboratory assays and the HScore should be performed in all severely ill COVID-19 patients to identify COVID-CS.