Similar to our observations in smokers compared to nonsmokers [9], other than the LAE up-regulation of TMPRSS2 in asthmatics overall compared to controls (p < 0.004, fold-change = 1.2), there were no other asthma-related changes in LAE expression among the genes related to coronavirus infection (p > 0.1, all comparisons). Here, TMPRSS2 is linked to asthma.