Pathway analysis using GSEA (Fig. 7B) showed that gastric cancer samples in the high-risk group were mainly enriched in Angiogenesis, Epithelial Mesenchymal Transition, Hedgehog signaling, Hypoxia, IL2/STAT5 signaling, Inflammatory Response, KRAS signaling up, NOTCH signaling, TGF-BETA signaling, NFKB/TNFA signaling. This evidence concerns the gene TGFB1 and gastric cancer.