Although it has been proposed that PCOS may result from reduced aromatase activity and subcutaneous AT have higher expression of CYP19 in comparison to visceral AT in morbidly obese men and premenopausal women [41], we cannot detect difference in mRNA levels of CYP19 between women with PCOS and non-PCOS. The gene discussed is CYP19A1; the disease is polycystic ovary syndrome.