From the result of DeepHBV with HBV integration sequences + TCGA Pan-Cancer, the binding sites of AR-halfsite, Arnt, Atf1, bHLHE40, bHLHE41, BMAL1, CLOCK, c-Myc, COUP-TFII, E2A, EBF1, Erra, Foxo3, HEB, HIC1, HIF-1b, LRF, Meis1, MITF, MNT, Myoga, n-Myc, NPAS2, NPAS, Nr5a2, Ptf1a, Snail1, Tbx5, Tbx6, TCF7, TEAD1, TEAD3, TEAD4, TEAD, Tgif1, Tgif2, THRb, USF1, Usf2, Zac1, ZEB1, ZFX, ZNF692, ZNF711 can be enriched in both attention-intensive regions of dsVIS and VISDB sequences. The gene discussed is NPAS2; the disease is cancer.