We noticed that the attention-intensive regions identified by the attention mechanism of DeepHBV with HBV integration sequences + TCGA Pan-Cancer strongly focused on the binding site of the HIC1 tumor suppressor gene, the circadian clock-related elements BMAL1, CLOCK, c-Myc, NAPS2, and other transcription factors such as TEAD and Nr5a2. Here, HIC1 is linked to cancer.