CXCL2 and neoplasm: To further investigate the association between the expression of CXCL2/3/8/9/10/11/14 and the diverse immune cell infiltration in CRC patients, we analyzed the relationship between CXC chemokines and sets of markers of various immune cells based on TIMER2.0, including tumor-associated macrophages (TAMs), neutrophils, DCs, and T helper 1 (Th1), Th2 and regulatory T (Treg) cells (Figure 8).