Hypoalbuminemia is believed to be a negative prognostic factor for patients undergoing various surgical procedures.[17] Prior studies found that low preoperative serum albumin levels can predict poor survival in patients with BUC[11,12,18]; however, to the best of our knowledge, our study is the first to investigate the relationship between the preoperative albumin level and OS in Chinese patients with BUC undergoing TURBT. The gene discussed is ALB; the disease is Hypoalbuminemia.