Finally, adiponectin levels are inversely and leptin levels directly correlated with prostate cancer grade in some cohorts (Saglam et al, 2003; Goktas et al, 2005; Karnati et al, 2017) suggesting that effects of SH‐BC‐893 on these adipokines (Fig 5) may contribute to its ability to suppress prostate cancer growth (Kim et al, 2016). This evidence concerns the gene LEP and Familial prostate cancer.