KLK3 and neoplasm: In univariate analysis, higher initial PSA level (P < 0.001), tumor volume 2-5 cc (P = 0.012), tumor volume > 5 cc (P < 0.001), presence of lymphovascular invasion (P < 0.001), presence of apex margin extension (P < 0.001), presence of basal margin extension (P < 0.001), presence of circumferential margin (CM) extension (P < 0.001), presence of vas deferens margin extension (P < 0.001), pT3a1 substage (P = 0.006), pT3a2 substage and presence of lymph node metastasis (P < 0.001) were associated with shorter BCR-free survival.