Considering that “T cell priming in lymph node” requires tumor-derived antigen presenting dendritic cells (APCs)8, intratumor gene expression of XCR1, Clec9a, Irf8, and Batf3, markers of APCs9–12, would be suitable markers that reflect the status of “T cell priming in lymph node”. This evidence concerns the gene IRF8 and neoplasm.