Using lymphocytes from tumor-draining lymph nodes, we found that IFNγ production was significantly increased in the control group when stimulated with FM3A cells compared to that when stimulated by MBT2 cells (MHC-matched negative control cells), and it was further significantly increased in the anti-PD-L1 mAb group compared to that in the control group (Fig. 4C). This evidence concerns the gene CD274 and neoplasm.