LYL1 and acute lymphoblastic leukemia: We found fusion cases clustered in close proximity to the early T- cell precursor (ETP) and immature Lim domain only 2/Lymphoblastic Leukemia Associated Hematopoiesis Regulator 1 (LMO2/LYL1) cases of the Liu et al. dataset (Supplementary Fig. 2a, b), suggesting fusion cases have a transcriptome similar to ETP-ALL despite their immunophenotype.