NOTCH1 and neoplasm: For example, lncRNA TUSC7 served as a tumor suppressor in pancreatic carcinoma through regulating miR-571a-5p expression [21]; lncRNA MACC1-AS1 accelerated the development of pancreatic carcinoma by activating PAX8/NOTCH1 pathway [22]; lncRNA PVT1 acted as an oncogenic lncRNA in pancreatic carcinoma by sponging miR-488 [23].