SHOX and RASopathy: In this study we have included 5 more genes that do not belong to the classical RASopathy genes but were included in a gene panel towards the molecular diagnosis of Noonan syndrome and other RASopathies by Institut für Medizinische Genetik (https://www.medgen.uzh.ch/de.html): ANKRD11 [72], FGFR3 [73–75], MEF2C [76, 77], SHOX [78–81], and SRCAP [68, 82].