NF1 and RASopathy: The current state of knowledge about the RASopathy interactome is mainly based on an integrated network presented at genome, interactome, and phenome levels [1]; Twelve causative genes and clinical symptoms were collected from OMIM and NCBI GeneReviews databases for 6 syndromes: NS, NSML, NF1, CFC, Legius and Costello syndrome.