FADS2 and Crohn disease: This is consistent with previous work that reported FADS2 to be associated with Crohn’s disease [56] and with the significantly increased expression of FADS2 (P = 0.009, Student’s t-test; Fig. 5f) that we observed in endoscopic pinch biopsies of Crohn’s disease patients compared to healthy donors using a previously published dataset [57].