Intriguingly, the divergent MHR sequence [94] of simian immunodeficiency virus (SIV) has only weak EB1-mimetic activity, while murine leukemia virus (MuLV) lack this activity, which correlates with the ability of these retroviruses to induce MT stabilization and engage CLIP170 to facilitate early infection, suggesting divergent capsid-based EB1 mimicry across retroviral species [75]. Here, MAPRE2 is linked to infection.