Photo‐documentation of CAM tumors developing from inoculated etoposide‐resistant RB355 cells (Fig. 6A), WERI‐Rb1 (Fig. 6B), and Y79 cells (Fig. 6C) and quantification of tumor weight (Fig. 7A,C,E) and tumor size (Fig. 7B,D,F) revealed that L1CAM‐depleted etoposide‐resistant RB cell lines develop significantly smaller tumors upon etoposide treatment than etoposide‐treated control cells. The gene discussed is L1CAM; the disease is neoplasm.