Photo‐documentation of CAM tumors developing from inoculated RB cells (Fig. 3A) and quantification of tumor weight (Fig. 3B) and size (Fig. 3C) revealed that L1CAM‐depleted RB cells develop significantly smaller tumors (Fig. 3A,C) than control cells, exhibiting lower weight and size (Fig. 3B,C). This evidence concerns the gene L1CAM and neoplasm.