Following infection, most animals had a transient increase of several cytokines and chemokines, including interferon (IFN)-alpha and MCP-1 (S2 Fig) peaking on day 1 (i.e., just before mAb administration), and a transient increase in C-reactive protein, ALT and AST, peaking on day 2 (S3 Fig). Here, CCL2 is linked to infection.