Although there are many potential etiologies of myocardial injury in the setting of COVID-19, including myocarditis [44], septic and/or stress cardiomyopathy [45, 46], or secondary hypoxic injury [47], our study did show that elevation in cTnI may be associated with the degree of multisystem organ dysfunction, and thus disease severity. The gene discussed is TNNI3; the disease is COVID-19.