ATP6AP1 levels were negatively associated with the levels of CD4+ T cells (Rho = –0.219, P = 2.76e-12), neutrophils (Rho = –0.194, P = 7.27e-10), type 2 T helper (Th2) cells (Rho =-0.205, P = 6.19e-11) and natural killer cells (Rho = –0.148, P = 2.67e-06) in BC tissues (Figure 3A). The gene discussed is CD4; the disease is breast cancer.