CD4 and infection: Across the endemic region, talaromycosis is estimated to have a pooled prevalence of 3.6% (range 0.13–19.63%) in people living with HIV/AIDS, with the greatest risk of infection in people with a CD4 cell count < 200 cells/mm3 (OR 12.68, 95%CI: 9.58–16.77) [1].