CCN2 and Duchenne muscular dystrophy: Moreover, CCN2 is found in the cytoplasm of necrotic and regenerating fibres and in active fibroblasts in the endomysial space of dystrophic human muscles and in mdx mice affected by Duchenne muscular dystrophy (DMD) (Morales et al. 2018; Song et al. 2017; Sun et al. 2008).