The amount of IFN-γ (PBMC only, 16.5 ng/mL; with SCLC cells, range 61–114 ng/mL) and IL-2 (PBMC only, 166.24 pg/mL; with SCLC cells, range 311.08–441.78 pg/mL), but not TNF-α, secreted into the co-cultures were accordingly increased with all the SCLC cell types employed (Fig. 2d). This evidence concerns the gene IFNG and small cell lung carcinoma.