FAP and neoplasm: A meta-analysis involving 15 studies which assessed FAP expression in 11 solid cancers by IHC concluded that FAP positivity is found in 50–100% of patients, and a higher FAP expression is associated with (1) increased local tumor invasion, (2) increased risk of LN metastases, and (3) decreased survival, in particular in cases where FAP is expressed in the malignant cells [15].