Angiogenic signalling is important for mesothelioma growth [76], and high expression levels of pro-angiogenic signalling molecules, such as VEGF, fibroblast growth factor (FGF)-1, transforming growth factor-β (TGF-β), platelet-derived growth factor (PDGF) and PDGF receptor-β, have been reported in mesothelioma tissue and many cell lines [76–78]. This evidence concerns the gene TGFB1 and mesothelioma.