JAM-A loss of expression (defined as H-score < 10) correlated with reduced overall survival in stages II and III CRC [HR: 1.43, 95% CI 1.02–2.02, p = 0.019 (Fig. 1H)] as well as in stage II only CRC [HR: 1.66, 95% CI 0.90–3.04, p = 0.037 (Fig. 1I)] in the Swiss cohort. The gene discussed is F11R; the disease is colorectal carcinoma.