LAMA1 and esophageal squamous cell carcinoma: In addition, to explore the effects of the circPDE3B/miR-4766-5p/LAMA1 axis on ESCC growth and metastasis in vivo, we established the following four EC9706 cell groups: NC (sh-NC), stable LAMA1 knockdown (sh-LAMA1), stable circPDE3B overexpression (circPDE3B and sh-NC), stable circPDE3B overexpression with LAMA1 inhibition (circPDE3B and sh-LAMA1).