In the following paragraphs, we describe how multiple factors such as YAP, TAZ [68, 69], BAP1 [27], Notch-1 [70], and noncoding RNAs, including miR-16-5p [71], miR-21-5p [71], miR-30a-5p [47], miR-129-3p [43], miR-129-5p [43], miR-452 [29], miR-584-5p [72], and lncRNA SNGH12 [42], regulate the expression of WWP1 in human cancer (Fig. 3). Here, WWP1 is linked to cancer.