Male (OR: 0.672, 95%CI: 0.558 ~ 0.809; P < 0.001), younger (OR: 1.026, 95%CI: 1.016 ~ 1.035; P < 0.001), higher LVEF (OR = 0.977, 95%CI: 0.971 ~ 0.984; P < 0.001) and preoperative statins (OR: 0.575, 95%CI: 0.466 ~ 0.709; P < 0.001) were associated with lower odds (i.e. protective) of PC-AKI, while CRP (OR: 1.009, 95%CI: 1.006 ~ 1.012; P < 0.001), diabetes (OR: 1.226, 95%CI: 1.012 ~ 1.484; P = 0.037) and excess volumes of CM (OR: 1.733, 95%CI: 1.156 ~ 2.596; P = 0.008) indicated higher odds (i.e. increased risk) of PC-AKI. This evidence concerns the gene CRP and pachyonychia congenita.