2005). In addition, fibronectin has been reported to be increased in many tumours, such as in mammary tumorigenesis and lung cancer (Han et al. 2006; Williams et al. 2008). Previous studies have found that fibronectin-1 (FN1) is up-regulated in GBM cells and may be an important key gene (Long et al. 2017). This evidence concerns the gene FN1 and glioblastoma.