Importantly, the decrease in Mtb survival/replication in these cells is not due to cell death of FL-galectin-8 or FL-galectin-9 overexpression cells; lactate dehydrogenase (LDH) release, a readout of cell death, increased in all cell lines over the course of a 72 h infection, but there was not increased cell death in FL-galectin-8 or FL-galectin-9 cells compared to controls (Fig. 7E). Here, LGALS8 is linked to infection.