AKT1 and nasopharyngeal carcinoma: Therefore, we established NPC cells with Notch2 overexpression using a lentiviral transfection technique and found that overexpression of Notch2 could improve the radiosensitivity of NPC cells in vitro by inhibiting cell proliferation, reducing viability, increasing G2/M-phase arrest, promoting apoptosis, and inhibiting the AKT/mTOR signaling pathway.