Consistent with this finding, the apoptosis rate of CNE-2 NPC cells overexpressing Notch2 alone or treated with radiotherapy alone was 11.98 ± 1.45% or 23.62 ± 1.96%, respectively but increased to 49.17 ± 1.17% in CNE-2 NPC cells overexpressing Notch2 and treated with radiotherapy (Figure 3(d)). This evidence concerns the gene NOTCH2 and nasopharyngeal carcinoma.