In a recent report, we have shown that PNA, like galectin-3, also binds to TF expressed by MUC1 on tumour cells and induces MUC1 cell surface clustering, leading to increased adhesion of tumour cells to the vascular endothelium and also to increased tumour cell homotypic aggregation for formation of tumour micro-emboli (12). This evidence concerns the gene LGALS3 and neoplasm.