In the standard of care group, a 64 years old man with diabete and hypertension included at the first visit with fever (38.7°C), high RT-PCT viral load (18 Ct) and inflammatory syndrome (CRP = 18.6 mg/L) was admitted at day 7 (20 Ct) for severe COVID-related pneumonia requiring oxygen (6 L/min) which recovered. The gene discussed is CRP; the disease is Hypertension.