To further explore the relationship among MALAT1, miR-655-3p, and ATAD2 in RB, we detected ATAD2 expression in Y79 and WERI-Rb-1 cells transfected with si-con, si-MALAT1, si-MALAT1 + anti-miR-con, or si-MALAT1 + anti-miR-655-3p. Here, ATAD2 is linked to retinoblastoma.