IL21R and inflammatory bowel disease: We uncovered that several genes were involved in the NF-kappa B signaling pathway, bacterial invasion of epithelial cells, Salmonella infection, inflammatory bowel disease, Rap1 signaling pathway, intestinal immune network for IgA production, T cell receptor signaling pathway, natural killer cell-mediated cytotoxicity, and NOD-like receptor signaling pathway components such as BCL10, LBP, PLCG1, ACTB, CLTB, MAPK12, FGFR4, IL21R, PLCG1, ITGB7, and NOD1 (Table S3).