Lower mRNA level of CD34 and αSMA were noted in CSWT treatment group, however, which were again elevated after inactivating PI3K/Akt pathway, as shown in Figure 3C (CD34: the HF group:1.90 ± 0.14; the HF + CSWT group: 1.24 ± 0.08; the HF + CSWT + LY294002 group: 1.53 ± 0.12, HF + LY294002 2.79 ± 0.10, p-values < 0.05; αSMA: the HF group: 2.85 ± 0.16; the HF + CSWT group: 1.22 ± 0.01; the HF + CSWT + LY294002 group: 1.75 ± 0.10; the HF + LY294002 group: 3.67 ± 0.14, p-values < 0.05). Here, AKT1 is linked to hydrops fetalis.