Next, to compare the immune response induced by SARS-CoV-2 in COVID-19 patients between with GI symptoms and in those without GI symptoms, we investigated the protein expression of pro-inflammatory cytokines IL-6, the SARS-CoV-2 IgM and IgG antibody, lymphocyte, NLR (cut off 3.04), CRP, SAA, and PCT. The gene discussed is CD40LG; the disease is COVID-19.