Munoz and Plevritis (2018) presented a predictive model using the estrogen receptor and human epidermal growth factor receptor 2 status to determine potential survival outcomes. Likewise, Chen et al. (2019) used five lncRNAs data in the TCGA database to obtain a five-lncRNA signature for use as an independent risk factor for OC recurrence. Furthermore, research on tumor microenvironments in cancer has gradually become popular. Yang et al. (2019) applied immune cell infiltration in cancers of the digestive system to process an effective diagnostic and prognostic model for these cancer types. Here, ESR1 is linked to cancer.