Particularly, CCNY was highly expressed in human cancers, such as hepatocellular carcinoma (HCC) cells, lung cancer tissues and cell lines, glioma cells, and colorectal carcinoma cell lines (Ying-Tao et al., 2005; Xu et al., 2010; Yue et al., 2011; Shi et al., 2018). This evidence concerns the gene CCNY and central nervous system cancer.