QKI and nervous system disorder: Previously, QKI is known for its important disease-causing contribution to human diseases, especially the neurological disorders, such as schizophrenia (Aberg et al., 2006), 6q terminal deletion syndrome (Backx et al., 2010), myelin disorders (Bockbrader and Feng, 2008), and Alzheimer’s disease (AD) (Farnsworth et al., 2016).