Although the detailed mechanisms of action in the development of DR are still unknown, involvement of mitochondrial dysfunctions with ROS formation and a decrease of the mitochondrial fusion protein mitofusin 2 (Mfn2) have been found in experimental models of this retinopathy (Eshaq et al., 2014; Duraisamy et al., 2019). Here, MFN2 is linked to retinal disorder.