PVT1 and cancer: We first filtrated ER lncRNAs with continuous status in multiple cancers (EA samples/ES samples > 2 or <0.5 in at least three cancer types) and obtained six EA lncRNAs (PVT1, PSMD5-AS1, FAM83H-AS1, MIR4458HG, HCP5, and GAS5) and three ES lncRNAs (CTD-2201E18.3, HCG11, and AC016747.3) (Figure 6A and Table 2).