Compared with other studies, this study supports the idea that EGFR-TKIs combined with TCM treatment can effectively delay the development of disease and prolong the survival of patients, which can provide more survival possibilities and basis for patients with advanced NSCLC, especially for the patients with exon 21 deletion mutation who have poor efficacy in the first generation of EGFR TKIs. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.