Studies have found that many extracts of TCM can reverse the acquired resistance of EGFR: such as astragaloside IV (17), resveratrol (18), curcumin (19), shikonin (20), dihydroartemisinin (21), Sophora flavescens (22), Taxus (23), Paris saponin (24), etc. Wang et al. through prospective cohort experiments found that the comprehensive treatment program of TCM was not inferior to the maintenance chemotherapy program of modern medicine in prolonging mPFS and mOS in patients with advanced NSCLC. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.