Compared with the >3 days admission-to-diagnosis time lag group, more patients in the ≤ 3 days group had splenomegaly, cytopenias, hypertriglyceridemia, hypofibrinogenemia, and hemophagocytosis, as well as elevated ferritin, TBil, ALT, APTT, PT, and INR within the first 48 h (all p-values <0.05). The gene discussed is GPT; the disease is Hemophagocytosis.