As shown in Figure 3, a higher expression of CD5 was observed in p1-positive cells (representing the VH 1-69 clone) as compared to p1-negative cells (the remaining CLL clones with IgBCR rearrangements differing from VH 1-69), both in CLL1 (Figure 3A) and CLL5 patient (Figure 3B), indicating that CD5 expression levels were related to the expression of VH1-69 rearrangement of IgBCR. Here, CD5 is linked to B-cell chronic lymphocytic leukemia.